Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Randomized Controlled Trial

Vigod et al, 2019. Brain Stimulation.

  • A randomised sham-controlled trial.
  • Transcranial direct current stimulation (tDCS) for depression in pregnant women.
  • 20 participants, all pregnant between 14-32 weeks.
  • There were no serious adverse effects, and no serious pregnancy complications.
  • End-point depression scores were lower, but not significantly so, in the tDCS group compared to the sham group.
  • 4 weeks after giving birth, 75% of those who had received tDCS were in remission, compared to only 12.5% for sham-tDCS.


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