Tuning brain networks: The emerging role of transcranial direct current stimulation on structural plasticity
Saviana Antonella Barbati, Maria Vittoria Podda, & Claudio Grassi. 2022. Frontiers in Cellular Neuroscience.
In this review, the authors recapitulate the most recent evidence around tDCS’ plastic effects bringing into focus its capability to trigger dendritic spine rearrangement in neurons, thus, changing neuronal wiring patterns. Currently, treatments based on boosting rewiring are explored by the scientific community to treat acute brain damage as well as permanent and progressive brain dysfunctions. A deeper comprehension of tDCS effects on rewiring and structural plasticity at the basis of neuronal network rearrangement will allow tDCS to be exploited therapeutically for treating brain pathologies characterized by the widespread brain wiring abnormalities.