Home ‑Administered tDCS for Major Depressive Disorder: Exploring thePredictive Value of EEG Biomarkers
João Marques Teixeira & Joana Costa, 2025. Revista Portuguesa de Psiquiatria e Saúde Mental.
- At-home self-administered tDCS was effective for treating major depression, with 63% of patients responding to treatment.
- Depression symptoms significantly improved over four weeks, alongside notable changes in frontal alpha asymmetry.
- A strong correlation (r = 0.63) was found between alpha asymmetry changes and symptom reduction.
- Pre-treatment frontal alpha asymmetry was a significant predictor of treatment response, supporting its use as a biomarker for personalized tDCS therapy.