Efficacy of Anodal Transcranial Direct Current Stimulation (tDCS) for the Treatment of Fibromyalgia: Results of a Randomized, Sham-Controlled Longitudinal Clinical Trial

Valle et al, 2009. The Journal of Pain Management.

  • A randomised, controlled longitudinal trial.
  • Transcranial direct current stimulation (tDCS) applied to the left primary motor cortex (M1) or dorsolateral prefrontal cortex (DLPFC), daily for 10 days.
  • 41 participants; all women with chronic, medically refractory fibromyalgia. The participants were randomly assigned to three groups: tDCS to the M1, tDCS to the DLPFC, or sham tDCS.
  • The M1 and DLPFC groups both showed improvement in pain and quality of life scores. The M1 group had long-lasting benefits, assessed both 30 and 60 days after the treatment.


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