Cathodal Transcranial Direct Current Stimulation of the Occipital cortex in Episodic Migraine: A Randomized Sham-Controlled Crossover Study

Ahdab et al, 2020. Journal of Clinical Medicine.

  • A double-blind and sham-controlled RCT that evaluated the efficacy of tDCS in patients with migraine.
  • Forty-two patients (N = 42) received either 3 days of daily cathodal tDCS over the occipital cortex (O1/O2), or sham tDCS.
  • 2 mA cathodal tDCS was given for 20 minutes per session, delivered with the Sooma tDCS device.
  • Results showed that active tDCS led to reductions in number of headache days, average daily pill consumption, and pain intensity.
  • The beneficial effects lasted for over two weeks.
  • The treatment was concluded to be effective, safe, and well-tolerated.


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