The effect of Sooma therapies are based on subtle adjustments of the brain function using a small electrical current. The therapy is targeted to the relevant neuronal pathways e.g. dorsolateral prefrontal cortex for depression in order to achieve a treatment response.
The main changes following the therapy happen at the cortical level of the brain and can be detected with e.g. EEG and fMRI. Recently, also changes in the deep brain regions have also been detected by the use of implanted electrodes.