What treatment outcomes tDCS gives for depression?

During last few years, transcranial direct current stimulation (tDCS) has become an established treatment option for the major depressive disorder. The latest meta-analysis concluded tDCS to be as effective as rTMS and antidepressant pharmaceuticals in primary care. Sooma Depression Therapy is a unique approach to tDCS that lets you treat more with less. Here we present a collection of our real-world treatment outcomes.


Sooma Depression Treatment uses transcranial direct current stimulation to modulate brain activity of the areas affected by depression. Research shows that tDCS is a safe, effective, and affordable treatment. tDCS can be prescribed as a mono-therapy or combined with pharmaceutical or psychosocial treatment options (read more here and here). Non-invasive tDCS relieves symptoms in depressed patients by modulating cortical excitability through a weak current. Meta-analyses have found active tDCS treatment to be superior to sham tDCS in depressed patients. Finally, tDCS is well tolerated, and no serious side effects have been reported. You can read more about the researched effects of tDCS here.

Treatment outcomes

Ten clinics have provided treatment outcomes from both unipolar and bipolar patients administered with Sooma Depression Treatment. Read more about the methodology, patient demographics and condition descriptions here and here. The outcome data reflect how the treatment is used in clinical practice today and what can realistically be expected as a treatment outcome. Here are the main findings:

  • The majority of patients experienced a marked improvement as a result of the treatment. 66% of the patients responded to the treatment.
  • There was a statistically significant and clinically meaningful difference in pre-treatment (Mean 27.3 ± Standard deviation = 7.2) and post-treatment scores (13.6 ± 8.0); p< 0.001.
  • 21% of the participants achieved complete remission.
  • The mean improvement in depression score was 54%. 9% of the patients improved by more than 75% whereas the score increased for 4% of the patients.
  • For the majority of patients, depression score improvement was between 50% and 75%.

Figure 1. Depression score reduction from baseline after Sooma Depression Therapy

On average, patients had severe depression when starting the treatment and ended up with mild depression after completion of treatment.

Figure 2. Depression severity change from baseline to post-treatment. 

  • According to patients, mood improvement and decreased anxiety were common changes in their condition.
  • Several patients reported increased activity and better functionality in daily life, as well as normalized appetite and sleep patterns.
  • Based on this study, the Sooma Depression Treatment is a safe and effective treatment for patients suffering from major depressive disorder.

Interested in learning more about this study? You can find more information on our blog, and if you have any questions about the tDCS treatment, visit us at #EPA2018!